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Boost upstream process development through real-time remote bioreactor monitoring.

Elevate your biologics yields with Culture Biosciences’ upstream process-development services powered by Console, our secure, cloud-connected bioprocessing software. With real-time, remote access to bioreactor data, generate in-process optimization recommendations to enhance biologics productivity and consistency.

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Bioprocessing is hard work. NexxysTM gets it done.

Nexxys provides on-demand bioprocess capacity for synbio and therapeutic protein labs, eliminating the need for additional capital investment or staffing.

Backed by deep bioprocess expertise and innovative cloud-connected bioreactor capabilities, Culture helps you enhance efficiency, boost productivity, and achieve your production goals faster and with greater confidence.

Service Bundles

Accelerate your bioprocess development with flexible, end-to-end bioreactor service bundles designed to meet you at every stage. From early feasibility to full process characterization, Nexxys combines rapid onboarding, cloud-based monitoring through Console, and embedded scientific expertise to help teams move faster without expanding internal infrastructure.

Every bundle includes:
  • Fast-Track Onboarding
  • Embedded Scientific Expertise
  • Live Console Access
  • Tailored Sampling
01

The Launchpad Process Feasibility & Baseline Data

Validation of process feasibility and performance

Best for teams looking for high-quality data without expanding physical footprints or established teams de-risking new processes off-site.

  • 4 Parallel Bioreactors

    Generate robust datasets instantly - no upfront CapEx

  • Process Translation Check

    Ensure shake-flask or bench results replicate in bioreactors

  • Baseline Establishment

    Define initial controls and performance

02

The Sprint Process Development Accelerated

Accelerated development of a scalable, optimized process

Best for teams ready to move quickly to a scalable, optimized process.

  • 12-24 Parallel Bioreactor DOEs

    Adaptive factorial designs with rapid learning cycles-to inform the next & accelerate convergence on optimal conditions

  • Rapid Learning Cycles

    Accelerated turnaround times allow for immediate follow-up runs, keeping your project momentum high

  • Validated Confirmation

    Final confirmation run enabling confident scale

  • Accelerated 20x Scale-Up

    Seamless translation from 250 mL to 5 L

03

The Insight Deep Process Collaboration

Complete, defensible process optimization and characterization

Best for bioprocesses requiring deep characterization and performance modeling.

  • 4+ Comprehensive Bioreactor DOEs

    Integrated experimental strategy spanning media inputs, and critical process parameters to fully characterize process

  • Interaction & Sensitivity Mapping

    Quantify main effects and interactions to distinguish true process drivers

  • Robustness & Risk Assessment

    Evaluate operating margins, sensitivity, and failure modes to support confident scale and transfer

Scalable, Expert Services Shaped to Your Process

Clone, strain & construct screening

Evaluate your bio clones, strains, and viral constructs with scalable flexibility using our advanced cell culture bioreactors. Our platform ensures efficient clone screening systems for optimal performance.

Process development

Accelerate timelines, optimize performance, and reduce risks in bringing biotherapeutics to market with our upsteam process development services and advanced bioreactor technology. By focusing our cell culture media optimization and development, we can help ensure your experiments deliver efficient and reproducible outcomes.

Process characterization

Use our advanced bioreactors and Design of Experiments (DoE) expertise to perform cell culture characterization prior to PPQ. Assess your upstream process in scale-down bioreactors that allow for enhanced model curvature, deeper variable exploration, and more robust process characterization development.

Bioprocess modeling and simulation

Scaling a bioprocess from R&D to manufacturing is challenging. Bioprocess modeling and simulation enables precise control over process conditions, improving efficiency and reducing variability. Our services offer a bioprocess digital twin approach to streamline development, leveraging advanced modeling to simulate and optimize conditions before running costly experiments.

Bioreactor scale-out

Run multiple experiments using our parallel bioreactor systems, which are cloud-connected 250mL and 5L bioreactors managed in our facility for high-throughput optimization to ensure process consistency, accelerated development, and seamless scalability. For those seeking an in-house solution, Stratyx250 provides a disposable 250mL bioreactor that users can implement directly in their own labs for greater control. While you will be limited on the number of experiments you can run on your own, you can pair our Stratyx platform running in your lab with the bioreactors running in ours.

Applications

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Synthetic Biology

Synthetic biology companies rely on efficient fermentation processes, strain optimization, and scalable bioprocessing to bring innovations to market. We offer two powerful solutions: our cloud-connected 250mL and 5L bioreactor service, providing high-throughput, managed fermentation capacity, and Stratyx250 - a disposable 250mL bioreactor for in-house experimentation. Whether refining microbial fermentation solutions, conducting strain screening, or optimizing synthetic biology applications, our flexible solutions can help you accelerate process development without costly infrastructure investments.

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Protein Therapeutics

Culture accelerates and de-risks process development, process characterization, material generation, and modeling for protein therapeutics in our cloud-connected bioreactor facility. By providing scalable protein therapeutic production solutions and efficient protein expression systems, we empower biotech researchers, pharmaceutical teams, and startups to rapidly optimize their processes and achieve consistent results. With Culture, you gain access to advanced tools and expertise that streamline upstream therapeutics.

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Viral Vectors

Culture accelerates and de-risks upstream process development for viral vectors by parallelizing experiments to reduce program bottlenecks.

Discuss which modular bioreactor service package fits your goals best.

Our collaboration with Culture Biosciences is providing an essential platform for streamlining media and process development. The capability to conduct simultaneous bioreactor experiments using Culture Bioscience's cloud-based bioreactors while accessing real-time data will enable greater flexibility and faster, more accurate information for decision making for us and our customers.

Luis

Luis Rodriguez , Ph.D.

R&D Manager, Bioproduction, FUJIFILM Biosciences

Culture feels like an extension of our own fermentation lab, not like a CRO.

shashway

Shashway Vajpeyi, Ph.D.

Fermentation Team Leader, Modern Meadow

Our bioreactors

At Culture, we custom-build our reactors to be cloud-connected and modular, making bioprocess scale-out, design, monitoring, and analysis as easy as possible.

250mL bench-scale single-use bioreactor

Benchtop bioreactor for process development

5L single-use bioreactor

Our modular bioreactors are designed to be easily scaled up or down.

Optimize your bioprocess with Culture