Services

Clone, strain & construct screening

Clone, strain & construct screening in our bioreactors

Evaluate your bio clones, strains, and viral constructs with scalable flexibility using our advanced cell culture bioreactors. Our platform ensures efficient clone screening systems for optimal performance.

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Benefits

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Comprehensive clone screening

Select the best cell clone or strain by evaluating larger experimental cohorts using our bioreactors. Make informed, data-driven decisions with our fleet of 250mL and 5L Culture bioreactors

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Cost-effective screening

Eliminate the need for capital equipment investment. Screen your bio clones, strains, and constructs using our state-of-the-art clone screening systems without additional infrastructure costs.

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Real-time monitoring and expert insights

Monitor transparent, real-time data from our cloud-connected bioreactors. With a >95% success rate across 22,000+ runs, our team of experts ensures seamless technology transfer and reliable results.

Capabilities

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Scaled-out bioreactor fleet

With over 300 bioreactors (250mL and 5L), Culture enables you to expand your experimental scope and achieve the best outcomes for your clone screening and bio fermentation process needs.

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Transparent, real-time monitoring

Our experiment data sharing platform enables your team to monitor process trends and analytical results in real time.

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BSL-1 and BSL-2 compliance

We culture and assay BSL-1 and BSL-2 organisms, ensuring versatility and compliance with industry standards.

Our facility

Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team.

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350+

250mL and 5L bioreactors

20,000+

Bioreactor runs to date

70+

Customers have used Culture's services to date

High quality & safety standards

Analytical capabilities

Microbial bioprocess
- Biomass quantification
- Metabolite analysis
Mammalian bioprocess
- Viability and cell counts

- Metabolite analysis
- Host cell protein
Protein
- Titer quantification
- Monomer/aggregation quantification
Viral vector
- Capsid titer
- Viral genome titer
- Empty/full ratio

Segregated modality suites

Mammalian
CHO and HEK
Viral vector (AAV)
AAV generated by HEK transfection
Microbial
Yeast, bacteria, and fungi
Media
Media recipes to customer specifications

Rigorous standards

Quality management systems (QMS)
Quality review of all runs and CAPA for major deviations
Safety & security
BSL-2 and SOC2 compliant

Our bioreactors

At Culture, we custom-build our modular reactors with cloud-connected controllers, making bioprocess scale-out, design, monitoring, and analysis as easy as possible.

250mL bench-scale single-use bioreactor

Benchtop bioreactor for process development

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5L single-use bioreactor

Bioreactor for process development and material generation

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Culture in your lab

Modular single-use bioreactors designed to be easily scaled up or down

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Optimize your bioprocess with Culture