Upstream process development and optimization
Accelerate timelines, optimize performance, and reduce risks in bringing biotherapeutics to market with our upstream process development services and advanced bioreactor technology. By focusing on cell culture media optimization and development, we can help ensure your experiments deliver efficient and reproducible outcomes.
Capabilities
Real-time monitoring, data collection, and precise control improve experimental outcomes and scalability.
Simultaneously test multiple variables to refine processes faster and more efficiently.
Advanced monitoring tools for power and experimental outcome analysis enable assessment of critical process parameters - such as growth rates, metabolite profiles, and protein yields - to promote data-driven decision-making.
Tailored support for formulating, testing, and scaling cell culture media to maximize productivity and reproducibility.
Our fleet of bioreactors is configurable to run multi-factor DOEs of nearly any size, applying systematic and data-driven experimental design to optimize bioprocess parameters efficiently and reduce variability across experiments.
Access a team of experienced bioprocess scientists to design, execute, and refine experiments for optimal outcomes.
Our facility
Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team.
350+
250mL and 5L bioreactors
20,000+
Bioreactor runs to date
70+
Customers have used Culture's services to date
High quality & safety standards
Analytical capabilities
- Metabolite analysis
- Metabolite analysis
- Host cell protein
- Monomer/aggregation quantification
- Viral genome titer
- Empty/full ratio
Segregated modality suites
Rigorous standards
Our bioreactors
At Culture, we custom-build our modular reactors with cloud-connected controllers, making bioprocess scale-out, design, monitoring, and analysis as easy as possible.
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We will be releasing a modular bioreactor system that you can install in your lab and control with ConsoleTM software.
